Cosmos Study December 16, 2025 Dual-Team Study Team A:Kersten Bartelt, RNNicholas Volker Team B:Tony Dunnigan, MDEric Barkley Key Findings Among patients with type 2 diabetes, GLP-1 use was associated with a 32% lower fracture risk for those with either osteopenia or osteoporosis
Matched-pair analysis of log-transformed data was used to compare conditions
References GLP-1 Agonists: Diving into the Data Marx N, Federici M, Schtt K, et al
Discussion In summary, this study reports on the rational design, synthesis, and in-depth biological evaluation of tumor-targeting ruthenium containing nanoreactors for glutathione oxidation catalysis in osteosarcoma cells with a 1% O 2 atmosphere
doi: 10.7554/eLife.87030.3 136 DenormeFRustadJLPortierICrandellJLde AraujoCVCodyMJet al